Explore the latest advances in nanoscale infrared spectroscopy and its applications across environmental and life sciences!
When: 2 November 2026, 09:00–13:30 CET
Where: LINXS, The Loop, Lund and online via Zoom
Organisers: LINXS theme Environment and Climate
More detailed programme will be announced soon!
Speaker
Dr. Francesco Simone Ruggeri, Associate Professor at Wageningen University, The Netherlands
Abstract
Nano-chemical Imaging and Spectroscopy of Biomolecular Processes
Biological processes rely on a wide class of biomolecular and macromolecular machines that have nanoscale physical dimensions and whose function emerges from a correlation between their chemical and structural properties. A fundamental objective of modern analytical methods is the comprehension of how physical-chemical properties and heterogeneity of single biomolecules underlie their role in cellular function and disease, moreover it also pave the way for the development of bio-inspired functional materials. While innovative nanoscale imaging methods have been developed to characterise biomolecular systems, imaging microscopies are to the most part chemically blind; thus, hampering the characterisation of inhomogeneous and complex systems.
The introduction of photothermal infrared nanospectroscopy (AFM-IR) has revolutionized the field of nano-chemical analysis in a wide-open range of fields, including biological, material and polymer sciences. Here, we will present an overview of our latest development and applications of AFM-IR in combination with advanced spectroscopic analysis and chemometrics, as a real breakthrough for the analysis of heterogeneous (bio-)molecular systems and materials down to the single molecule level.
Overall, our aim is to expand the capabilities of nano-analytical science to shed light on the structure-activity relationship of biomolecules and functional materials design.
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