Highlights advances in time-resolved synchrotron techniques, including X-ray spectroscopy, scattering, serial crystallography, and multimodal approaches used to probe structural and functional dynamics across multiple length and timescales.

Scientific sessions focus on the challenges and strategies of performing time-resolved experiments, including sample preparation and delivery, reaction triggering and synchronization, high-throughput data collection, and analysis of large dynamic datasets. Discussions will emphasize how these approaches bridge the gap between static structural information and mechanistic understanding.

PROGRAMME – Tuesday 22 September

09:00 – 10:45 — Small Angle X-ray Scattering: SAXS in Time-resolved Experiments

09:00-09:05 Dr Fatima Herranz (MAX IV Laboratory) - Opening comments

09:05-09:35 Dr Tiago N. Cordeiro (Universidade NOVA de Lisboa) - Probing Conformational Dynamics in Flexible Macromolecular Assemblies

09:35-09:55 Dr Firoz Malayil Kalathil (MAX IV Laboratory) - Millisecond Structural Kinetics of Elastin Phase Separation at CoSAXS Using Laser-Induced Temperature Jumps

09:55-10:10 Dr Byungnam Ahn (MAX IV Laboratory) - From Nanosecond to Femtosecond: Fiber-Based High-Power Laser Delivery for CoSAXS

10:10-10:40 Ms Fatemeh Sabzian Molaei (Umeå University) - Time-resolved X-ray solution scattering: from experimental challenges to interpretation of protein dynamics in solution

10:45-11:15 Coffee break

11:15 – 12:00 — Time-resolved Serial Synchrotron Crystallography

11:15-11:20 Dr Carl Ekström (MAX IV Laboratory) - Opening comments

11:20-11:50 Torbjörn Nur Olsson (University of Gothenburg) - Picosecond time-resolved crystallography captures a terahertz-induced quench-like redistribution of fluctuations in a protein crystal

11:50-12:00 Mrs Courtney Tremlett (University of Exeter) - Water Networks Coordinate Catalytic Dynamics in GmhA