Pandemics and Alertness Co-leader WG3 (Complementary and enabling techniques), LINXS Fellow

Researcher at the Swedish BioMS and SciLifeLab Integrated Structural Biology (ISB) mass spectrometry platforms & Department of Clinical Sciences Lund (IKVL), SciLifeLab Group Leader, Division of Infection Medicine, Lund University, Lund, Sweden

Lotta Happonen studied biotechnology and genetics at the University of Helsinki, Finland, where she obtained her PhD in 2012 in structural virology using single particle cryoEM and X-ray crystallography as the main research methods. She joined Lund University initially as a postdoctoral researcher, and she is currently a PI and SciLifeLab Group Leader of a research group in Structural Infection Medicine (STRIME) at the Division of Infection Medicine. The methodological interests and research focus of her are to integrate cryoEM, X-ray crystallography, crosslinking and hydrogen-deuterium exchange mass spectrometry with quantitative proteomics in order to advance the understanding of the molecular basis of infections. These efforts have paved the way for research activities of deciphering the structure of host-pathogen protein complexes, with the aim of providing novel interfaces to target for diagnostic, preventive, and therapeutic opportunities.

In addition to leading her research at the Division of Infection Medicine, she has an affiliation with the Swedish National Infrastructure in Biological Mass Spectrometry (BioMS) Lund node and the SciLifeLab Integrated Structural Biology platform (ISB), where she leads and develops the crosslinking mass spectrometry research and workflows. She is an elected board member and former President of the Swedish Proteomics Society (SPS); a national organisation promoting proteomics research in Sweden, and the Swedish connection to the European and global proteomics organizations.