Maggie Holme
Maggie Holme
Soft Matter in Life Core Group member and co-leader of WG1 (Higher complexity in lipid self-assembly), LINXS Fellow
Assistant Professor, Chalmers University of Technology, Gothenburg, Sweden
Maggie and her group focus on applying neutron and X-ray scattering techniques to quantify the structural arrangement of lipid species in a range of liposome, lipid nanoparticle, and extracellular vesicle systems. She couples this with a range of complementary techniques including in vitro assays, single particle techniques, sup-population separation methods, surface techniques, lipidomics, and microscopy. By combining these techniques, she and her group aim to uncover the role that lipid chemical composition and physical arrangement plays in the bioactivity of synthetic and naturally-derived vesicles and LNPs, and in how we can better understand how these particles interact with cells and with model membranes of increasing complexity. Maggie obtained her PhD in Nanoscience at Basel University, Switzerland, studying lipid vesicles as cardiovascular delivery vectors, and the morphology of human coronary arteries using absorption/phase-contrast X-ray tomography. She completed post docs at Imperial College London, UK (2013-2017) and Karolinska Institutet, Sweden (2017-2022), studying lipid self-assembled structures and their applications in drug delivery and diagnostics. In 2023 she began her independent research group at Chalmers University of Technology, Department of Life Sciences, in the Division of Chemical Biology.
