Pandemics and Alertness member WG1 (Understanding the virus) and WG3 (Complementary and enabling techniques), LINXS Fellow

Department of Medical Biochemistry and Biophysics, Wallenberg Centre for Molecular Medicine Umeå, Umeå Centre for Microbial Research, Molecular Infection Medicine Sweden, SciLifeLab Umeå, Sweden

Lars-Anders Carlson received his PhD from the Ruprecht Karls University Heidelberg. In his PhD work in Heidelberg and at the Max Planck Institute of Biochemistry, he used cryo-electron tomography to study HIV-1 budding. As a postdoc with James Hurley (University of California, Berkeley) he used membrane reconstitution methods to study HIV assembly and the human ESCRT proteins. At Umeå University, he leads a research group that focusses on the replication of positive-strand RNA viruses. This large and diverse group of viruses contain human pathogens such as dengue virus, Chikungunya virus, TBE virus, SARS-CoV-2, poliovirus and rhinoviruses. All positive-stand RNA viruses replicate on remodelled cytoplasmic membranes, hence having a strong link to cellular membrane trafficking. His group studies these phenomena by a combination of methods including biochemistry, cell biology and cryo-electron tomography.